A. I. Cuza University of Iaşi

Bioinformatics

Course nameBioinformatics CodeCS3210O1
Class Undergraduate, 2008 - 2011 Package 5
Level Licenţă Year 3 Semester 2 Status Optional
Hours per weekTotal hours per semesterTotal hours of individual workCreditsEvaluation typeTeaching language
CSLPr
2 0 2 0 48 168 5 P ro
Taught byAcademic and scientific title, name
Associate Professor, PhD, Liviu Ciortuz
Required courses
ObjectivesUnderstanding the basic technics in the analysis of genetic sequences
General thematics
  1. Fundamental notions in molecular biology
  2. Alignment of pairs of DNA/protein sequences
  3. Multiple alignment of DNA/protein sequences
  4. Phylogenetics
  5. Hidden Markov Models (HMMs)
  6. Alignment of pairs of DNA/protein sequences using pair-HMMs
  7. Multiple alignment of DNA/protein sequences using profile-HMMs
  8. Analysis of RNA sequences
  9. Motif in identification in genetic sequences
Seminary / Laboratory thematicsSolving exercises and problems
Implementation of some of the presented algorithms and their applications
Presentation of recent papers in the area of bioinformatics
Teaching methodsSlides on video-projector
Bibliography
  • "Biological Sequence Analysis'', Richard Durbin, Sean Eddy, Anders Krogh, Graeme Mitchison; Cambridge University Press, 1998
  • "Problems and Solutions in Biological Sequence Analysis", Borodovsky, Ekisheva, Cambridge University Press, 2006
  • "Theory and Mathematical Methods in Bioinformatics", Shyiy Shen, Jack Tuszynski, Springer, 2008
  • "An Introduction to Bioinformatics Algorithms", Neil Jones & Pavel Pevzner; MIT Press, 2004
  • "Computational Genomics", Nello Cristianini, Matthew Hahn, Cambridge University Press, 2006.
Evaluationconditions
criterias
modes
formulaBasis (1 point) +  1st written work (4.5 points)  + 2nd written work (4.5 points)

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